Our laboratory aims to create functional organs with three-dimensional structures by using human induced pluripotent stem (iPS) cells to generate different cell types. Our research examines how tissue structures form during organ development and regeneration, and the mechanisms that regulate these processes. We seek to contribute to regenerative medicine, disease modeling, and understanding developmental mechanisms.
Research using cells and tissues
In addition to human iPS cells, our research uses patient-derived cells and animal models.
Our research areas include the liver, bile ducts, pancreatic cancer, and cartilage. For example, liver research investigates how three-dimensional tissue structures form during development and, based on these findings, works to generate liver organoids from human iPS cells. We are also working to reproduce tubular structures such as bile ducts and the hepato-biliary connection, and to build liver disease models.
Organoids, regenerative medicine, and disease models
Organoids are research models that reproduce some features of tissue structure and function in cell culture.
Our research includes efforts toward creating organs for regenerative medicine, building disease models, and analyzing the mechanisms of organ development and regeneration.
Learn more about the laboratory
Information about research, laboratory members, and news is available on existing pages within the mirror site.
Original site and mirror site
The original site is accessible only from within Japan. This mirror site can be accessed worldwide, allowing visitors outside Japan to view information about the laboratory.